A comparison of Esmolol and Labetalol for Attenuation of Sympathomimetic Responses to Laryngoscopy and Intubation

Both Labetalol and Esmolol in low doses are not effective in attenuation of sympathomimetic response to laryngoscopy and endotracheal intubation. ABSTRACT: Objective: The study was designed to Compare esmolol and labetolol for attenuation of sympathomimetic responses to laryngoscopy and intubation. Materials & Methods: 80 patients were randomly divided into two groups by prospective randomized single blind study, 40 patients received labetolol 0.5mg/kg and other patients received esmolol 0.25mg/kg. The baseline heart rate, BP, Spo2 were recorded & Compared. Conclusion: both Labetalol ( 0.25mg/kg ) and Esmolol (0.5 mg/kg ) in low doses are not effective in attenuation of sympathomimetic response to laryngoscopy and endotracheal intubation .

To evaluate the efficacy between 0.15mg/Kg and 0.25mg/Kg of iv labetalol in the suppression of haemodynamic response to extubation - IJCA

Ivabradine versus propranolol given orally in microlaryngoscopic surgeries in attenuating stress response: A comparative prospective double blind randomized study - ScienceDirect

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Comparision of Esmolol and Labetalol in Low Doses for Attenuation of Sympathomimetic Response to Laryngoscopy and Intubation

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