Scientists discover unique imaging technique to view synapse proteins

Researchers have devised a new way to clearly image synapse proteins, which they hope will faciliate future treatment for schizophrenia and autism.

Scientists discover unique imaging technique to view synapse proteins

DNA-PAINT imaging of synaptic proteins: (a) scheme of protein labeling

pan-ExM reveals synapse ultrastructure in dissociated neurons. a, NHS

The lipid transporter ORP2 regulates synaptic neurotransmitter release via two distinct mechanisms - ScienceDirect

Super-Resolution Imaging of the Extracellular Space in Living Brain Tissue - ScienceDirect

Imaging and Biosimulation Platform to Advance Drug Discovery and Development for CNS Diseases

Development and maintenance of vision's first synapse - ScienceDirect

How can I measure brain acetylcholine levels in vivo? Advantages and caveats of commonly used approaches - Mineur - 2023 - Journal of Neurochemistry - Wiley Online Library

Technique can image individual proteins within synapses, MIT News

Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX

Surprising Discovery: MIT Neuroscientists Find That Adult Brain Is Filled With Millions of “Silent Synapses”

LIVE-PAINT achieves sparse labeling using reversible peptide–protein