The Safety of High Dose Labetalol in the Pregnant Population

Hypertension in pregnancy is one of the leading causes of maternal mortality and rapid treatment is critical. Treatment of emergent hypertensive crises in pregnancy is limited to only three medications, one of which is labetalol. Current literature recommends a daily maximum intravenous labetalol dose of 300 mg per day. However, this maximum dose has not been studied in pregnancy where higher doses may be required.

Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial - The Lancet

LABETALOL HYDROCHLORIDE tablet, film coated

Nifedipine In Pregnancy: Safety, Usage, Dosage And Side Effects

Frontiers Pharmacokinetic data in pregnancy: A review of available literature data and important considerations in collecting clinical data

Obstetric and Fetal Pharmacology, Article

Hypertension in Pregnancy

These highlights do not include all the information needed to use LABETALOL HYDROCHLORIDE INJECTION safely and effectively. See full prescribing information for LABETALOL HYDROCHLORIDE. LABETALOL HYDROCHLORIDE IN SODIUM CHLORIDE injection , for

Full article: Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials

Labetalol and asthma: Possible risks, and complications

Labetalol Tablets: Package Insert